Brendan Keating, United States

Brendan Keating, Is an Associate Professor in the Division of Transplantation, Department of Surgery, and The Institute of Systems Genetics, New York University (NYU) Langone Health, USA, with adjunct positions in University of Pennsylvania (UPenn) and the Children’s Hospital of Philadelphia. He received his D.Phil. (Ph.D.) in molecular genetics from Christ Church College, at the University of Oxford, UK with his thesis completed in the Department of Clinical Medicine, and the Wellcome Trust Center for Human Genetics. He completed a post-doctoral fellowship at the Institute of Translational Medicine and Therapeutics (ITMAT) and faculty position in Departments of Pediatrics and Surgery at UPenn, and he was also a visiting Scientist at the Wellcome Trust Sanger Institute, Cambridge, UK.

A major research interests focus on the analyses of polymorphisms of transplant donor and recipient’s genomes, to discover and validate genomic signals that underpin graft rejection and post-transplant complications in allotransplant, and pig to human xenotransplant settings. He instigated the formation of an international genomics consortium (iGeneTRAIN) for large-scale genomic studies using > 55,000 patient DNA samples from a number of international transplant studies which he has funded through an NIH-NIAID U01. Dr. Keating also leads a Phase IV clinical trial for the early detection, diagnoses and treatment of influenza in transplant households using wearable devices (NCT06161454).

Dr. Keating is also PI of a prospective funded study looking at post-transplant outcomes in 12 North American pediatric renal transplant centers (NCT03719339), which is funded by NIH-NICHD, and of a Heart Transplant multiomics NIH funded R01. Dr. Keating also leads multiomic studies in pig to human xenotransplant studies being conducted in NYU and University of Pennsylvania, and has created the largest pig to human xenotransplant biobank to date spanning sample types for up to 13 different omic studies.